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Low IQ And Family History Linked To Therapy-Resistant Schizophrenia

According to a new study by scientists, people having a family medical history of schizophrenia and men with low IQ are more tend to struggle with therapy-resistant schizophrenia compared to other mental disorders. The research was led at Karolinska Institutet in Sweden and the findings were published in the journal Molecular Psychiatry. The researchers stated that these findings can be important in efforts to develop new drug treatments that advance cognition. Reportedly, schizophrenia is a mental condition that impacts how a person feels, thinks, and behaves. The signs include abnormal behavior and speech, disorientation, hallucinations, and other cognitive troubles.

Over 30% of those identified with the condition do not react to existing antipsychotic drugs. This group suffers from TRS (treatment-resistant schizophrenia), which is a medical condition that is linked with a greater peril for suicide and noteworthy health costs. A person might be identified with TRS following failing to respond to a minimum two rounds of different antipsychotic drugs. During this research, the scientists followed over 24,000 Swedish adults for at least 8.5 Years, counting around 4,800 who experienced TRS. They utilized several national population catalogs like patient, multi-generation, prescribed drug, and military conscription records to collect and link the data. The study findings demonstrated that those who had many relatives with schizophrenia and men with a low IQ at 18 Years of age were at considerably higher perils of having therapy-resistant schizophrenia compared to treatment responsive schizophrenia.

On a similar note, recently, a study showed that combination therapy may be helpful in schizophrenia. Merging certain kinds of two antipsychotic agents in the preservation treatment of schizophrenia is linked with a lesser peril of relapse than utilizing monotherapy. The study was published in the journal JAMA Psychiatry. The present treatment guidelines must modify their definite recommendations discouraging all antipsychotic polypharmacy, as per the researchers.

Ramona Bohn
Ramona Bohn Author
Writer & Author At Industry News Digest

Having more than 4 years of experience in the industry, it has been a couple of years for Ramona to be at Industry News Digest. She is responsible for anything that takes place in the Health Department, making her the sole leader of the department. She has also grabbed a couple of certificates to justify her role. Ramona appreciates a cool coffee shop, finds learning incredibly motivating, and is an aspirant urban farmer in her apartment.

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